Abstract #1291

Time-encoded Arterial Spin Labeling for Renal Perfusion Quantification Covering the Whole Kidneys

Zihan Ning¹, Zhensen Chen², Shuo Chen¹, Hualu Han¹, Long Zhao³, Rui Wang⁴, Dongyue Si¹, Huiyu Qiao¹, Rui Shen¹, and Xihai Zhao¹

¹Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China, ²Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ³Department of Radiology, Beijing Anzhen Hospital, Beijing, China, ⁴Department of Radiology, Peking University First Hospital, Beijing, China

Synopsis

Keywords: Kidney, Perfusion, renal perfusionWe performed a series of optimization on the encoding scheme, pseudo-continuous ASL (pCASL) parameters, and post-processing of time-encoded pCASL (te-pCASL), then proposed Time-encoded Arterial Spin labeling to cover the whole Kidneys (TASK) to achieve multiple time-points renal perfusion measurement efficiently. With G_ave of 0.4-0.6 mT/m and G_max/G_ave around 10, Walsh-Hadamard encoding scheme, and retrospective registration, TASK was able to provide accurate and reproducible RBF and ATT measurement covering the whole kidneys with single 5-min scan.

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