Abstract #1317
Similarity-driven motion-resolved reconstruction for ferumoxytol-enhanced whole-heart MRI of congenital heart disease patients
Ludovica Romanin1,2, Bastien Milani1, Christopher W. Roy1, Aurélien Bustin1,3,4, Salim Si-Mohamed1,5,6, Milan Prsa7, Tobias Rutz8, Estelle Tenisch1, Juerg Schwitter8,9, Matthias Stuber1,10, and Davide Piccini1,2
1Diagnostic and Interventional Radiology, University Hospital of Lausanne (CHUV), Lausanne, Switzerland, 2Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, 3IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux – INSERM U1045, Pessac-Bordeaux, France, 4Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Pessac, France, 5INSA-Lyon, CNRS, Inserm, CREATIS, Université de Lyon, Villeurbanne, France, 6Département de Radiologie, Louis Pradel Hospital, Hospices Civils de Lyon, Bron, France, 7Woman-Mother-Child Department, Lausanne University Hospital and University of Lausanne, Division of Pediatric Cardiology, Lausanne, Switzerland, 8Heart and Vessel Department, Lausanne University Hospital and University of Lausanne, Service of Cardiology, Lausanne, Switzerland, 9Cardiac MR Center, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 10Center for Biomedical Imaging (CIBM), Lausanne, Switzerland
Synopsis
Keywords: Heart, Motion Correction
Ferumoxytol-enhanced free-running whole-heart MRI allows for a comprehensive evaluation of the cardiovascular anatomy in 3D. A similarity-driven multi-dimensional binning algorithm (SIMBA) has been proposed as a fast and efficient reconstruction of such data, by clustering and selecting motion-consistent information. In this work, we extend the SIMBA reconstruction to make use of the inherent redundancy of motion-consistent information using a compressed-sensing reconstruction, in which sparsity is maximized by the integration of inter-cluster non-rigid 3D motion-fields. With this new framework we demonstrate improved image quality, increased coronary sharpness and vessel conspicuity.
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