Abstract #1326

Stability of Elevated Wall Shear Stress in Patients with Bicuspid Aortic Valve: Insights from a Multi-Year 4D Flow MRI Follow-Up Study

Anthony Maroun¹, Michael Scott¹, Haben Berhane¹, Justin J. Baraboo¹, Kelly Jarvis¹, Bradley D. Allen¹, Alex J. Barker², and Michael Markl¹

¹Department of Radiology, Northwestern University, Chicago, IL, United States, ²Department of Radiology, University of Colorado, Aurora, CO, United States

Synopsis

Keywords: Flow, Valves4D Flow MRI can identify aortic regions exposed to high wall shear stress (WSS) compared to age and sex-matched controls. This concept, known as WSS ‘heatmaps’, has recently shown potential to improve risk stratification in patients with bicuspid aortic valve (BAV). We examined the reproducibility of heatmaps in a cohort of 20 stable BAV patients with five consecutive 4D flow MRI scans and found no significant change over time. In addition, we found high reproducibility of WSS patterns and regions of elevated WSS across scans. Our findings, therefore, suggest that heatmaps can serve as a robust BAV risk measure.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.