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Abstract #1328

Development and Validation of a Radiomics Model in Differentiating Sinonasal Mucosal Melanomas from Sinonasal Lymphomas

Shengyong Li1, Linying Guo2, Jing Zhang1, Yang Song3, Shengjian Zhang4, Rifeng Jiang5, Guang Yang1, and Zuohua Tang2
1Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China, 2Department of Radiology, Eye & ENT Hospital of Shanghai Medical School, Fudan University, Shanghai, China, 3MR Scientific Marketing, Siemens Healthcare, Shanghai, China, 4Department of Radiology, Shanghai Cancer Center of Shanghai Medical School, Fudan University, Shanghai, China, 5Department of Radiology, Fujian Medical University Union Hospital, FuZhou, China

Synopsis

Keywords: Head & Neck/ENT, MultimodalSinonasal mucosal melanomas (SNMM) are clinically more aggressive than its cutaneous counterpart and presented markedly poor prognosis. To differentiate sinonasal melanomas from sinonasal lymphomas, a radiomics model was built using features from multi-parametric MRI, including T1-weighted imaging (T1WI), T2 weighted imaging (T2WI), DWI and C-T1WI. In this multicenter retrospective study, 189 patients diagnosed with SNMMs or sinonasal lymphoma were enrolled from three institutions. The proposed model achieved AUCs of 0.884 and 0.870 in the internal and external validation set, respectively.

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