Abstract #1346

Carotid plaque predicts progression of intracranial atherosclerosis: A MR imaging-based community cohort study

Miaoxin Yu¹, Dandan Yang², Runhua Zhang¹, Yong Jiang¹, Huiyu Qiao³, Xihai Zhao³, Gaifen Liu¹, and Yongjun Wang¹

¹Department of Neurology, Beijing Tiantan Hospital, Beijing, China, ²Department of Radiology, Beijing Geriatric Hospital, Beijing, China, ³Tsinghua University, Beijing, China

Synopsis

Keywords: Head & Neck/ENT, AtherosclerosisIntracranial atherosclerotic disease progression is associated with recurrent stroke risk. In the present study, we investigated the association between carotid plaque and intracranial atherosclerosis progression in stroke-free participants using MR vessel wall imaging. In 312 participants recruited from a community cohort, we found that carotid plaque was independently associated with intracranial atherosclerosis progression during around 3-years’s follow-up. Our findings suggest that carotid plaque may be an effective predictor for intracranial atherosclerosis progression.

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