Abstract #1359

In-vivo parcellation of human subcortex by diffusion and anatomical MRI

Tonima Ali^1,2, Jinglei Lv^1,2, Marshall Dalton^2,3, Steve Kassem⁴, Arkiev D'Souza^2,5, and Fernando Calamante^1,2,6

¹School of Biomedical Engineering, The University of Sydney, Sydney, Australia, ²Brain and Mind Centre, The University of Sydney, Sydney, Australia, ³School of Psychology, The University of Sydney, Sydney, Australia, ⁴Neuroscience Research Australia, Sydney, Australia, ⁵Translational Research Collective, The University of Sydney, Sydney, Australia, ⁶Sydney Imaging, The University of Sydney, Sydney, Australia

Synopsis

Keywords: Multi-Contrast, Diffusion/other diffusion imaging techniques, Brain, Gray matter, Segmentation, NeuroWe integrated the information from structural and diffusion MRI from a group of healthy subjects, to develop a data-driven parcellation of the human subcortex. We first identified the data features that are sensitive to the micro-architectural variabilities within subcortex and then segregated specialised sub-regions with discernible properties. Our parcellated sub-regions demonstrated remarkable similarities to known nuclei and sub-structures within striatum, globus pallidus, and thalamus. Our parcellation has also identified regions which are known to have distinct anatomical and functional properties but that are yet to be explicitly added to extant human brain atlases.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.