Abstract #1386

Signal recovery around DBS leads using 2D MSI

Gehua Tong¹, John Thomas Vaughan, Jr.^1,2, and Sairam Geethanath^2,3

¹Biomedical Engineering, Columbia University, New York, NY, United States, ²Columbia Magnetic Resonance Research Center, Columbia University, New York, NY, United States, ³Accessible MR Laboratory, BioMedical Engineering and Imaging Institute, Dept. of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mt. Sinai, New York, NY, United States

Synopsis

Keywords: Parkinson's Disease, Pulse Sequence Design2D MSI was tested for recovering the closest layer of off-resonant signals near a DBS lead. The effects of slice thickness and RF profile were measured in an ASTM gel phantom with an in-plane DBS lead. Increasing the slice thickness from 1.5x to 2.5x the lead diameter reduced the apparent lead width by 8.35% and increasing the time-bandwidth product of the RF pulse by four times improved SSIM with a reference TSE image by 88.5%. A trade off between bin definition and echo times limited signal recovery at a given bin bandwidth (800 Hz / 9 bins).

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