Abstract #1391

Improved Visualization of the Medial Medullary Lamina with Phase Prior Reconstruction in Quantitative Susceptibility Mapping

Alexandra Grace Roberts^1,2, Ilhami Kovanlikaya², Brian Koppel³, Pascal Spincemaille², Thanh Nguyen², and Yi Wang^1,2

¹Electrical Engineering, Cornell University, Ithaca, NY, United States, ²Radiology, Weill Cornell Medicine, New York, NY, United States, ³Radiology, Mount Sinai Hospital, New York, NY, United States

Synopsis

Keywords: Parkinson's Disease, BrainMorphology Enabled Dipole Inversion (MEDI) is an iterative reconstruction algorithm for Quantitative Susceptibility Mapping (QSM) that is effective in suppressing artifacts by exploiting the magnitude image as a morphological prior. Use of a phase prior such as the local field to determine the $$$L_1$$$ regularization term results in improved visualization of the medial medullary lamina as measured by the contrast-to-noise ratio and was preferred by a radiologist over the magnitude prior in each case.

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