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Abstract #1416

Improvement of Brain MRS at 7T Using a Wireless RF Array

Akbar Alipour1, Gaurav Verma1, Andrew Frankini1, Bradley N Delman1, and Priti Balchandani1
1Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States

Synopsis

Keywords: High-Field MRI, SpectroscopyMagnetic resonance spectroscopy (MRS) can particularly benefit from substantial enhancement in SNR and spectral resolution at ultra-high field (UHF ≥7T), enabling improved quantification of metabolites. However, at 7T wavelength effects cause a highly inhomogeneous transmit magnetic field in the human brain, with lower transmit efficiency in the posterior-fossa manifesting as signal dropout in this region. Recently, we reported advantages of a surface-applied inductively-coupled radiofrequency array to improve transmit efficiency and signal sensitivity at 7T MRI focusing on cerebellum and inferior temporal lobes. Here we demonstrate the feasibility and effectiveness of in-vivo MRS using the array in human cerebellum at 7T.

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Keywords