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Abstract #1423

Whole-brain 3D B1+ mapping in under 30 seconds: compressed-sensing accelerated SA2RAGE

Gabriele Bonanno1,2,3, Tom Hilbert4,5,6, Patrick Liebig7, José P. Marques8, and Tobias Kober4,5,6
1Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Bern, Switzerland, 2Magnetic Resonance Methodology, Institute of Diagnostic and Interventional Neuroradiology, University of Bern, Bern, Switzerland, 3Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland, 4Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, 5Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 6LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 7Magnetic Resonance, Siemens Healthcare GmbH, Erlangen, Germany, 8Donders Institute for Brain Cognition and Behaviour, Radboud University, Nijmegen, Netherlands

Synopsis

Keywords: High-Field MRI, RF Pulse Design & Fields, B1+ mapping

To fully exploit the strengths of UHF imaging, accurate B1+ mapping is essential, ideally in 3D with sufficient coverage and high dynamic range. However, resulting scan times on the order of minutes are problematic, especially with the prospect of increased clinical use of 7T imaging. We implemented a compressed sensing readout and reconstruction for the SA2RAGE technique yielding <30 s scan time for a whole-brain, 4-mm isotropic resolution B1+ map. We tested different acceleration factors, validated against the GRAPPA-accelerated reference protocol of ~2 min and found <0.05 relative B1+ difference in most regions of the brain.

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Abstract Presentation Video

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