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Abstract #1426

An Optimized RF Coil for Sensitive 31P Magnetic Resonance Spectroscopic Imaging of the Human Brain and Cerebellum at 7T.

Johnny Chris Der Hovagimian1,2, Pedram Yazdanbakhsh2,3, Marcus Couch2,3,4, and David A. Rudko1,2,3
1Department of Biomedical Engineering, McGill University, Montreal, QC, Canada, 2McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, Montreal, QC, Canada, 3Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada, 4Siemens Healthcare Limited, Montreal, QC, Canada

Synopsis

Keywords: High-Field MRI, RF Arrays & SystemsAn optimized RF coil was constructed for 7T, Phosphorus (31P) Magnetic Resonance Spectroscopic Imaging (MRSI) of the whole brain including the cerebellum. The cerebellum is a region not well covered by most existing 31P coils. The design consisted of an optimized 16-rung high-pass birdcage transmit coil and a 24-channel phased array receive coil affixed to a custom head-shaped former. The coil provided high sensitivity to 31P signals across the whole brain and brainstem. In vivo 31P 3D CSI experiments showed high quality spectra with regional PCr SNR values near the cerebellum comparable to values near the brain centre.

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