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Abstract #1430

Accuracy, Precision, and Reproducibility of 3D Whole Heart Simultaneous T1 and T2 Mapping Based on Multi-parametric SAVA: A Comparison Study

Dongyue Si1, Rui Guo2, Daniel A. Herzka3, and Haiyan Ding1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China, 2School of Medical Technology, Beijing Institute of Technology, Beijing, China, 3Department of Radiology, Case Western Reserve University, Cleveland, OH, United States

Synopsis

Keywords: Myocardium, Tissue Characterization

MR parametric mapping including T1 and T2 enabled quantitative evaluation of changes of myocardium. We previously proposed a time-efficient technique for 3D free-breathing simultaneous T1 and T2 mapping based on multi-parametric SAturation recovery and Variable flip Angle (mSAVA). This study evaluated the accuracy, precision, and reproducibility of mSAVA in comparison with conventional 2D sequences. mSAVA achieved good accuracy, between that of MOLLI and SASHA, and better precision and reproducibility than SASHA for T1 measurements. T2 measured by mSAVA had better precision and reproducibility than both GraSE and bSSFP T2. mSAVA offers a promising option for myocardial tissue characterization.

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