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Abstract #1432

Accelerated 3D Stack-of-Spiral Cardiac Quantitative Susceptibility Mapping: Noninvasive Measurement of Heart Oxygenation in a Breath-Hold

Jiahao Li1,2, Pablo Villar-Calle3, Hannah Agoglia3, Nicole Liberman3, Thanh D. Nguyen2, Yi Wang1,2, Jiwon Kim3, Jonathan W. Weinsaft3, and Pascal Spincemaille2
1Biomedical Engineering, Cornell University, Ithaca, NY, United States, 2Radiology, Weill Cornell Medicine, New York, NY, United States, 3Medicine, Weill Cornell Medicine, New York, NY, United States

Synopsis

Keywords: Heart, OxygenationA breath-holding non-cardiac gated 3D stack-of-spiral data acquisition scheme was developed to continuously sample the data for cardiac quantitative susceptibility mapping. Compared to the previously proposed navigator-based prospective Cartesian acquisition, the accelerated spiral sequence can be done within 20 seconds breath-holds, leading to over a 20-fold reduction in scan time. The spiral QSM as well as the navigator QSM were performed on cohorts of healthy volunteers and COVID-19 survivors, showing well aligned quantification results on the differential blood oxygenation between the right and left heart.

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Keywords