Keywords: MSK, MSK, Total hip arthroplastyMicromotion at interfaces in modular total hip arthroplasties (THAs) induces corrosion and generation of adverse local tissue reactions (ALTRs), potentially leading to premature failure. The flexural rigidities (FR) of THA femoral stem trunnions retrieved from revision surgery were correlated with MRI metrics and histopathological outcomes. Increased FR was associated with osteolysis and a reduced synovial response, while a lower FR was associated with granulomas, different synovitis types, and tissue necrosis. These results indicate that MRI can serve as a useful biomarker of the local tissue response around THA.
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