Abstract #1442

Diagnostic performance of Rapid Whole-body MRI with uniformly fat-suppressed T2-weighted imaging for multiple myeloma

Rianne A van der Heijden¹, Timothy M Schmidt², Scott B Reeder^1,3,4,5,6, and Ali Pirasteh^1,3

¹Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, ²Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, United States, ³Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ⁴Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, ⁵Department of Medicine, University of Wisconsin-Madison, Madison, WI, United States, ⁶Department of Emergency Medical Physics, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Skeletal, PET/MR, Multiple MyelomaIn this study we evaluated the diagnostic performance of whole-body T2-weighted imaging with uniform 2-point Dixon fat-suppression for the detection of multiple myeloma. Furthermore, we evaluated the added sensitivity, change in disease stage, and change in treatment plan with the sequential addition of DWI and FDG PET. T2-Dixon demonstrated higher sensitivity than both DWI and PET. Adding DWI did not change stage or treatment plan. However, the addition of PET did change the treatment plan in one patient with extra-osseous disease. Whole-body PET-MRI with T2-Dixon is a promising and efficient tool for assessment of multiple myeloma.

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