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Abstract #1476

Improved differentiation of BI-RADS 4 breast lesions based on ultrafast dynamic contrast-enhanced MRI radiomics and artificial neural network

Lingsong Meng1, Xin Zhao1, Jinxia Guo2, Lin Lu1, Meiying Cheng1, Qingna Xing1, Honglei Shang1, Yan Chen1, Penghua Zhang1, and Xiaoan Zhang1
1The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2General Electric (GE) Healthcare, MR Research China, Beijing, Beijing, China

Synopsis

Keywords: Breast, RadiomicsImproving the assessment of Breast Imaging Reporting and Data System (BI-RADS) 4 lesions can avoid unnecessary biopsies. As an emerging field, radiomics has been successfully explored as a means to aid decision-making for the diagnosis and risk stratification of several kinds of cancers1-4. In this study, we combined radiomics features extracted from ultrafast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) (using the Differential sub-sampling with cartesian ordering (DISCO) technique) with an artificial neural network (ANN) to improve diagnostic performance in assessing BI-RADS 4 lesions and evaluate the potential to avoid unnecessary biopsies.

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