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Abstract #1488

31P and 1H MRS for in vivo metabolic profiling of diffuse large B-cell lymphoma

Katharina J Wenger1,2,3,4, Seyma Alcicek1,2,3, Ulrich Pilatus1, Dennis C Thomas1,2,3, Elke Hattingen1,2,3,4, Florian Buettner4, Andreas Loth5, and Thomas Oellerich2,3,4,6
1Institute of Neuroradiology, University Hospital Frankfurt, Frankfurt am Main, Germany, 2University Cancer Center Frankfurt (UCT), Frankfurt am Main, Germany, 3Frankfurt Cancer Institute (FCI), Frankfurt am Main, Germany, 4German Cancer Research Center (DKFZ) Heidelberg, Germany and German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt am Main, Germany, 5Department of Oto-Rhino-Laryngology, University Hospital Frankfurt, Frankfurt am Main, Germany, 6Department of Hematology/Oncology, University Hospital Frankfurt, Frankfurt am Main, Germany

Synopsis

Keywords: Cancer, Tumor, lymphoma, multiomics, MR-SpectroscopyWith the presented protocol, key metabolites related to different metabolic profiles of aggressive lymphomas (such as lactate, alanine, as a surrogate for pyruvate, as well as choline components) can be detected in vivo in a clinical setting.

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Abstract Presentation Video

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