Keywords: Vessel Wall, Blood vesselsType-B aortic dissection represents a serious medical emergency with up to a 50% associated 5-year mortality caused by thoracic aorta, dissection-associated aneurysmal (DAA) degeneration, and rupture. Unfortunately, conventional diagnostic methods cannot distinguish high-risk DAAs that benefit from surgical intervention from stable DAAs. Our goal is to use DAA stiffness measured with magnetic resonance elastography (MRE) as a biomarker to distinguish high-risk DAAs from stable DAAs. This is a feasibility study using MRE to 1) measure stiffness in hydrogel phantoms with human-like dissection geometries and 2) demonstrate the first successful application of MRE to the thoracic aorta of a human volunteer.
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