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Abstract #1516

Contrast-to-noise ratio of carotid artery perivascular adipose tissue on MRI: A potential indicator for carotid vulnerable plaque

Shuwan Yu1, Ran Huo2, Huiyu Qiao1, Zihan Ning1, Rui Shen1, Ning Xu1, and Xihai Zhao1
1Center for Biomedical Imaging Research, Tsinghua University, Beijing, China, 2Peking University Third Hospital, Beijing, China

Synopsis

Keywords: Atherosclerosis, Inflammation, Carotid artery PVAT, Vulnerable plaques

Inflammation of carotid artery perivascular adipose tissue (PVAT) is associated with atherosclerotic disease. This study investigated the association between carotid artery PVAT and atherosclerotic plaques using multi-contrast MR vessel wall imaging. The contrast-to-noise ratio (CNR) of PVAT was measured on TOF MRA images. We found that the CNR of carotid artery PVAT measured by TOF MRA is independently associated with carotid vulnerable plaque features, suggesting that the CNR of PVAT might be a potential indicator for vulnerable atherosclerotic plaques.

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Keywords