Keywords: Neurodegeneration, Magnetization transfer, Multiple system atrophyThe magnetic transfer (MT) MRI imaging has long been used for quantifying neuromelanin containing nucleus, but its ability of quantifying the magnetization exchange between free water and macromolecules has also allowed its potential usage in detecting white matter changes. Patients with multiple system atrophy has unique pathological changes in pontocerebellar regions. In this study, we have not only found significant increase of MT contrast in MCP regions of MSA, but also proved significant correlation between this alteration and brainstem or cerebellar atrophy, which might offer new insights for future studies.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords