Abstract #1550

Quantitative evaluation of the spinal cord compression in patients with cervical spondylotic myelopathy using synthetic MRI

Xiangyu Tang¹, Haoyue Shao¹, Weiyin Vivian Liu², Qiufeng Liu¹, and Wenzhen Zhu¹

¹Radiology department, Tongji hospital, Tongji medical college, Huazhong University of science and technology, Wuhan, China, ²MR Research, GE Healthcare, Beijing, China

Synopsis

Keywords: Spinal Cord, Quantitative Imaging, Synthetic MRI, Cervical spondylotic myelopathyThe present study for the first time applied synthetic MRI in diagnosis of patients with cervical spondylotic myelopathy. Multiple relaxation maps (T1, T2 and PD maps) and contrast-weighted images were obtained in a single scan of synthetic MRI. Our study demonstrated that T1 and T2 relaxation times of spinal cord at maximal compression level (MCL) changed with a grade dependent difference and T1_MCL value could sensitively reflect the microstructural alteration of compressive spinal cord and even MCL at grade I, Moreover, T1_MCL and T2_MCL value was related to clinical scores and diameter values of the spinal cord at MCL.

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