Keywords: Spinal Cord, Spinal CordThis study analyzed spinal cord diffusivity in CSM subjects treated with metallic spinal fusion decompression. Metal-artifact-suppressed diffusion-weighted MRI were collected on 38 CSM subjects and 25 controls. Diffusivity was analyzed as a function of cohort and level instrumentation (instrumented, non-instrumented, and adjacent segment). In addition, the impact of mJOA symptom scores and duration since the fusion procedure on diffusivity were modeled. Multi-linear mixed effects models accounted for demographic variations and multiple-measures (at different cord levels) within each subject. The results of the study identified consistent reductions in diffusivity due to the presence of fusion instrumentation.
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