Abstract #1565

Histogram analysis of Intravoxel incoherent motion (IVIM) in differentiating high-grade glioma and solitary brain metastasis

Yifei Su¹, Jinxia Guo², Junhao Wang¹, Rui Cheng³, Chunhong Wang³, Liangliang Hao⁴, Hongming Ji³, Yexin He⁴, and Cheng Xu⁴

¹The Fifth Clinical Medical College of Shanxi Medical University, Taiyuan, China, ²GE Healthcare, MR Research, Beijing, China, ³Department of Neurosurgery, Fifth Hospital of Shanxi Medical University, Taiyuan, China, ⁴Department of Radiology, Fifth Hospital of Shanxi Medical University, Taiyuan, China

Synopsis

Keywords: Tumors, Cancer, high grade glioma, solitary brain metastasisWe aim to explore the value of intravoxel incoherent motion (IVIM) in differentiating high-grade glioma (HGG) and solitary brain metastasis (SBM) by using histogram and first-order texture analysis in combination with the structural lesion feature. Results showed there were significant higher skewness (Dfast, f) and kurtosis (Dslow, f), and significant lower entropy (Dslow, f) and mean (f) in HGG solid tumor region as well as significant lower mean (f) in HGG peritumoral edema zone. Clear tumor margin in T2-weighted imaging help improve the differentiation when integrated with the IVIM parametric values.

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