Abstract #1578

Differentiation of High-Grade Gliomas from Solitary Brain Metastases in the Peritumoral Edema: using Combined Synthetic MRI and 3D-pCASL

Xin Ge^1,2, Yuhui Xiong³, Min Li⁴, Xiaodong Wang⁵, and Jing Zhang²

¹Second Clinical School, Lanzhou University, Lanzhou, China, Lanzhou, China, ²Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China, Lanzhou, China, ³GE Healthcare MR Research, Beijing, China, Beijing, China, ⁴GE Healthcare MR Enhancement Application, Beijing, China, Beijing, China, ⁵Department of Radiology, General Hospital of Ningxia Medical University, Yinchuan, China, Yinchuan, China

Synopsis

Keywords: Tumors, TumorThe main work of our research was to investigate the difference of quantitative MR metrics from synthetic MRI and 3D-pCASL including T₁, T₂, PD, CBF, and the multiparametric strategies that contained more than one of the metrics between high-grade gliomas (HGGs) from solitary brain metastases (SBMs) in the peritumoral edema. We found that the T₁, T₂, and CBF were useful metrics for differentiating HGGs from SBMs which were easily confounded with HGGs in daily diagnosis. Furthermore, combining T₁, T₂, and CBF further improved their diagnostic performance.

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