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Abstract #1602

Optimized MR Fingerprinting OPTIMUM in vivo in the vicinity of a metallic implant at low field

Gabriel Zihlmann1,2, Mathieu Sarracanie1,2, and Najat Salameh1,2
1Center for Adaptable MRI Technology (AMT center), Department of Biomedical Engineering, University of Basel, Allschwil, Switzerland, 2AMT center, Institute of Medical Sciences, school of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, United Kingdom

Synopsis

Keywords: Low-Field MRI, MR FingerprintingMagnetic susceptibility changes at interfaces induce artefacts, and hence compromises MRI diagnostic value. Low-Field (LF) MRI is inherently less sensitive to susceptibility artifacts making it suitable for imaging near metallic implants. In addition, the dispersion in T1-contrast is enhanced at LF. To evaluate the potential for new contrast mechanisms, quantitative imaging would be key if acquisition times are compatible with clinical constraints. In that context, model-based multi-parametric OPTIMUM was performed in a healthy volunteer’s forearm carrying a titanium plate from plate-osteosynthesis surgery. Performance of two signal models, one oblivious to intravoxel dephasing and the other accounting for it was compared.

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