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Abstract #1607

Insensitive to Off-Resonance 3D T1/T2 Mapping SPGR/bSSFP using Dictionary-Matching: Application to the Prostate at 3T

Ronal Coronado1,2, Carlos Castillo-Passi3,4, Cecilia Besa2,5, and Pablo Irarrazaval2,6
1Biomedical Imaging Center-Universidad Catolica de Chile, Santiago, Chile, 2Millenium Institute for Intelligent Healthcare Engineering, Santiago, Chile, 3Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, Santiago, Chile, 4King's College London, London, United Kingdom, 5Departamento de Radiologia-Universidad Católica de Chile, Santiago, Chile, 6Department of Electrical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

Keywords: Quantitative Imaging, ProstateBalanced Steady State Free Precession (bSSFP) has been successfully used to estimate T2 maps (DESPOT2), but bSSFP is prone to off-resonance artifacts. These artifacts affect the reconstruction of the T2 maps. We propose a dictionary-matching reconstruction using the signal model of bSSFP and spoiled gradient echo (SPGR). We tested this approach with simulation, 3D phantom and 3D in-vivo prostate acquisitions. In all of them, the off-resonance banding artifacts are greatly reduced, which is reflected in reduced NRMSE values. This method allows using a faster sequence with high SNR to quantify complicated body regions like the prostate.

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Keywords