Keywords: Quantitative Imaging, Quantitative Imaging, T1 mapping In phantom study, SPGR-MOLLI acquisition scheme was optimized for abdominal T1 mapping in EOB-MRI, which was applied to clinical patients to measure ECV of the spleen and paraspinal muscle obtained 4 min and 25 min after the contrast administration. ECV obtained from contrast-enhanced CT within 3 months from EOB-MRI was used as reference standard. ECVs calculated from EOB-MRI showed significant agreements with those obtained from CT with ICCs of 0.9 and 0.74 for 4 min and 25 min, respectively (p<0.0001), which suggested that our T1 mapping protocol is appropriate and applicable to ECV measurement in EOB-MRI similarly with contrast-enhanced CT.
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