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Abstract #1615

Over-estimation of T2 with radial sampling: Identification, understanding and strategies to mitigate the bias.

Nadège Corbin1,2, Aurélien J. Trotier1, Sylvain Miraux1, and Emeline J. Ribot1
1Centre de Résonance Magnétique et Systèmes Biologiques UMR5536 CNRS/University of Bordeaux, Bordeaux, France, 2Wellcome Centre for Human Neuroimagin, UCL Queen Square, Institute of Neurology, University College of London, London, United Kingdom

Synopsis

Keywords: Quantitative Imaging, Relaxometry, radial sampling

Quantitative MRI protocols can benefit from radial trajectory sampling to reduce the acquisition time. However we identified a bias in T2 relaxometry studies conducted with radial imaging. After in-depth analysis aiming at further our understanding of the underlying mechanisms, we propose some guidelines to mitigate this bias. The error depends on the range of T2 present in the object of interest and its geometry, the number of spokes and the trajectory of the sequence. Parallel imaging and compressed sensing help reducing the bias.

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Keywords