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Abstract #1621

Multiparametric quantitative MRI mapping using ultrahigh-field strength

Zaheer Abbas1, Markus Zimmermann1, Dominik Ridder1, Ana-Maria Oros-Peusquens1, and N. Jon Shah1,2,3,4
1Institute of Neuroscience and Medicine 4, Jülich, Germany, 2Institute of Neuroscience and Medicine 11, INM-11, JARA, Forschungszentrum Jülich, Jülich, Germany, 3JARA - BRAIN - Translational Medicine, Aachen, Germany, 4Department of Neurology, RWTH Aachen University, Aachen, Aachen, Germany

Synopsis

Keywords: Quantitative Imaging, BrainMeasurement of quantitative, tissue-specific MR properties such as water content or relaxation times using quantitative-MRI at clinical field strength (1.5T and 3T) is a well-explored topic. Established methods for water content mapping are based on the variable flip-angle (VFA) approach. However, transition to ultrahigh field strength remains challenging due to significantly increased RF field inhomogeneity. Here, we demonstrate a novel VFA method to acquire quantitative water content and relaxation times at 7T with full brain coverage and 1x1x1.5 mm resolution within 7 min. Accuracy and precision of the parametric maps is demonstrated by comparison to already reported results.

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