Keywords: Quantitative Imaging, Data Acquisition, Data analysis
Carotid quantitative high-resolution MR vessel wall imaging, such as T1- and T2-mapping, showed a great potential to stratify vulnerable plaques. This study proposed a 3D large-coverage carotid quantitative imaging solution including bright- and black-blood quantitative VWI protocol and an efficient post-processing pipeline. The proposed protocol was in excellent agreement with standard mapping in measuring T1 (R2=0.99) and T2 (R2=0.94) validated by phantom study. The volunteer experiment proved that there was no significant difference in measuring T1 (1103.89±50.86 ms vs. 1125.34±50.39 ms, P=0.26) and T2 (31.23±1.50 ms vs. 31.69±1.54 ms, P=0.21) of muscle between the proposed protocol and clinical reference mapping.
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