Abstract #1631

Highly efficient simultaneous joint T1-T2 mapping for isotropic resolution 3D knee imaging

Dabne Barrera¹, Nicolás Garrido^1,2, Andrew Phair³, Ronal Coronado^1,4, Haikun Qi⁵, René M Botnar^1,2,3, and Claudia Prieto^1,3,4

¹Millennium Institute for Intelligent Healthcare Engineering (iHEALTH), Santiago, Chile, ²Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, ³King's College London, London, United Kingdom, ⁴Electrical Engineering Department, Pontificia Universidad Católica de Chile, Santiago, Chile, Santiago, Chile, ⁵ShanghaiTech University, Shanghai, China

Synopsis

Keywords: Quantitative Imaging, Osteoarthritis

Recently, a free-running T₁-T₂ 3D radial imaging sequence was proposed to enable simultaneous acquisition of T₁ and T₂ maps of the hearth with isotropic spatial resolution. Here, we sought to investigate the feasibility of this sequence with 1 mm³ isotropic spatial resolution for the characterization of articular cartilage in scan time of ~4 min. The proposed approach was evaluated on a standardized phantom and in-vivo in healthy subjects, showing good agreement with reference values.

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