Abstract #1638

Quantitative Susceptibility Mapping of Human Kidney Using Multi-echo Gradient Echo with Dual TR: A Preliminary Study

Yingjie Mei¹, Yihao Guo², Qiang Liu¹, Kan Deng³, Peng Wu⁴, Chenggong Yan⁵, Yikai Xu⁵, and Yanqiu Feng¹

¹School of Biomedical Engineering, Southern Medical University, Guangzhou, China, ²Deparment of Radiology, Hainan General Hospital, Haikou, China, ³Philips Healthcare, Guangzhou, China, ⁴Philips Healthcare, Shanghai, China, ⁵Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China

Synopsis

Keywords: Quantitative Imaging, Quantitative Susceptibility mapping, kidney

QSM of human kidney remains challenging due to chemical shift and respiratory motion. We utilized a dual-TR based multi-echo gradient echo (GRE) sequence and proposed an in-phase method to solve nonconvex optimization problem in water-fat separation for QSM of human kidney. The kidney QSM data were successfully acquired and calculated in all four volunteers. The kidney QSM implemented in our study could provide valuable imaging markers for the assessment of pathophysiological changes of kidney diseases.

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