Keywords: Relaxometry, Liver, T2*, liver iron contentMRI T2* relaxometry is a reliable method for assessing liver iron overload. To develop a fully automatic T2* relaxometry data processing method for assessing liver iron overload, we promoted a semi-automatic parenchyma extraction to an automatic approach by introducing a modified TransUNet on R2* map for the segmentation of whole liver. The proposed method showed excellent liver segmentation performance on the internal and external test sets and yielded T2* measurements highly consistent with those by the semi-automatic method. This fully automatic approach will enable an efficient and reliable measurement of liver T2* for assessing hepatic iron content in clinical practice.
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