Keywords: Cancer, LungAs a promising approach to analyze tumor heterogeneity through image features, habitat analysis has been applied for a variety of tumors, such as lung adenocarcinoma (LUAD). To our knowledge, the previous applications, mainly based on CT and PET images, would potentially hold a limited impact on the power of habitats analysis. In this study, our goal is to extend the applications of habitat analysis in LUAD with multi-parametric MR images, which would be obtained routinely longitudinally and to guide specific therapies.
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