Abstract #1675

Continuous-time random walk diffusion model combined with VI-RADS to predict muscle invasion of bladder cancer

Wei Wang¹, Ke Xue², Yongming Dai², and Jianxing Qiu¹

¹Department of Radiology, Peking University First Hospital, Beijing, China, ²MR Collaboration, Central Research Institute, Shanghai United Imaging Healthcare, Shanghai, China

Synopsis

Keywords: Cancer, Bladder, diffusion/other diffusion techniquesAccurately differentiation of MIBC from non-muscle-invasive bladder cancer (NMIBC) is essential for selecting the optimal treatment plan and obtaining a better prognosis for BCa patients. In this study, the role of the CTRW model, VI-RADS and their combination in characterizing MIBC was evaluated. The CTRW parameters combined with VI-RADS could provide significantly better diagnostic performance for MIBC determination than the VI-RADS score alone. The CTRW model could serve as a compliment to VI-RADS and provide added value for predicting muscle invasion of bladder cancer.

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