Abstract #1689

Ferumoxytol-Enhanced 5D ROCK-MUSIC with Low-rank Tensor Reconstruction: Initial Feasibility in Pediatric Congenital Heart Disease

Zixuan Zhao¹, Hsu-Lei Lee², Guowen Shao¹, Zhengyang Ming¹, Fei Han³, Dan Ruan¹, Anthony Christodoulou², J. Paul Finn¹, and Kim-Lien Nguyen^1,4

¹University of California, Los Angeles, Los Angeles, CA, United States, ²Cedars-Sinai Medical Center, Los Angeles, CA, United States, ³Siemens Health Solutions, Los Angeles, CA, United States, ⁴VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States

Synopsis

Keywords: Heart, Cardiovascular, Congenital Heart Disease, FerumoxytolROCK-MUSIC is a 4D whole heart MRI pulse sequence that has shown promise for fast imaging in pediatric congenital heart disease (CHD) without dependence on the ventilator respiratory gating signal. Recent research in cardiac multitasking with low rank tensor (LRT) reconstruction allows for decomposition of cardiorespiratory motion. In this preliminary work, we showed that LRT reconstruction can be applied to the ROCK-MUSIC acquisition to enable higher temporal resolution with cardiorespiratory resolved imaging. When compared to L1-ESPIRiT, the LRT approach is able to achieve comparable image quality.

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