Abstract #1696

Cardiac Gated, Ferumoxytol-Enhanced MR Angiography of the Aorta with a Flexible k-space Trajectory: Initial Results

J Paul Finn^1,2,3, Takegawa Yoshida^1,2, Arash Bedayat^1,2, Kim-Lien Nguyen^2,3,4, Xiaodong Zhong⁵, and Gerhard Laub⁶

¹Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States, Los Angeles, CA, United States, ²Diagnostic Cardiovascular Imaging Laboratory, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States, Los Angeles, CA, United States, ³Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States, Los Angeles, CA, United States, ⁴Division of Cardiology, David Geffen School of Medicine at UCLA and VA Greater Los Angeles Healthcare System, Los Angeles, CA, United States, Los Angeles, CA, United States, ⁵Siemens Healthineers, Los Angeles, CA, United States, ⁶DrLaubconsulting LLC, Los Angeles, CA, United States

Synopsis

Keywords: Heart, CardiovascularContrast enhanced MRA of the aorta is typically performed without cardiac gating, greatly limiting its value in the aortic root and its more widespread utilization. We implemented a cardiac gated sequence for breath-held MRA of the thoracic aorta with flexible contrast during the steady-state distribution of ferumoxytol and compared it to ungated MRA with similar resolution. The resulting images were compared for definition of the aortic annulus, leaflets and ascending aorta. The gated sequence performed significantly better than the ungated sequence for all measured parameters and holds promise as a high quality alternative to gated CTA in appropriate clinical circumstances.

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