Abstract #1713

Characterization of a controlled cortical impact brain injury and metabolic changes using magnetic resonance spectroscopy

Asamoah Bosomtwi¹, Roxan Ara², Fengchong Kong², Yujiao Lu³, and Krishnan M DHANDAPANI³

¹Georgia medical College, Augusta, GA, United States, ²Georgia Cancer Center, Augusta University, Augusta, GA, United States, ³Neurosurgery, Augusta University, Augusta, GA, United States

Synopsis

Keywords: Traumatic brain injury, Spectroscopy

Traumatic brain injury (TBI) diagnosis and treatment is a top priority for military medicine. Several preclinical models of TBI have been developed to help elucidate the etiology of brain injury but these models typically depend on behavioral outcomes to indicate injury severity. In this project we used magnetic resonance spectroscopy (MRS) to investigate a noninvasive, longitudinal technique to detect changes in brain metabolites after TBI

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