Keywords: Nerves, DiabetesThe objective of this study was to evaluate the atrophy pattern of the hippocampus subregions in Parkinson's disease with type 2 diabetes mellitus patients (PDDM) patients based on the 3DTI sequence and FreeSurfer software. The FreeSurfer provides extensive and automated neuroimaging analysis and has been successfully used to precisely segment the hippocampus. In this study, automated volumetry of hippocampal subfields in PDDM patients was performed, compared with Parkinson's disease without diabetes mellitus (PDND) patients and healthy controls . The results showed that PDDM patients have hippocampal subregions atrophy, especially in the right fimbria, right GC-ML-DG and right CA4.
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