Keywords: Neurodegeneration, Neurodegeneration, Atlas, NigrosomeIron accumulation in Nigrosome 1 (N1) may represent an important biomarker in neurodegenerative disorders but its small dimension and the vanishing swallow tail sign in patients make the segmentation of this region challenging. We propose a probabilistic atlas of N1 created on a multimodal (T1-w and T2*-w) template using ROIs that were manually drawn on 0.6mm-isotropic T2*-weighted images of twenty healthy subjects. Its usability and accuracy were tested on four additional subjects by comparing the mean N1 susceptibility and T2* obtained using the atlas to those obtained from manual ROIs and by measuring their geometrical proximity.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords