Abstract #1742

NODDI maximum abnormal signal area histogram analysis for differentiation between glioblastoma Multiforme and solitary brain metastasis

Jinbo Qi¹, Xiaoyue Ma¹, Peipei Wang¹, Eryuan Gao¹, Guohua Zhao¹, Kai Zhao¹, Yang Song², Huiting Zhang³, Ankang Gao¹, Jie Bai¹, Yong Zhang¹, and Jingliang Cheng¹

¹Department of MRI, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, ²Magnetic Resonance Scientific Marketing, Siemens Healthineers Ltd., Shanghai, China, ³Magnetic Resonance Scientific Marketing, Siemens Healthineers Ltd., Wuhan, China

Synopsis

Keywords: Tumors, Diffusion/other diffusion imaging techniques, Neurite orientation dispersion and density imagingWe aim to explore the value of neurite orientation dispersion and density imaging (NODDI) maximum abnormal signal area histogram analysis for differentiation between glioblastoma Multiforme (GBM) and solitary brain metastasis (SBM). 50 patients with GBM and 50 patients with SBM confirmed by surgical pathology were enrolled and underwent MR examination. Result showed that multiple histogram parameters can significantly distinguish GBM from SBM, and the performance of logistic regression model is better than that of optimal single parameter.

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