Abstract #1743

Combination of DKI and IVIM for differentiating True Progression from Pseudoprogression of Glioma with Postoperative Radiation Therapy

Pei Dang¹, Xueying Huang², Zhihua Yang³, Aijun Wang², Lidong Wang⁴, Yuhui Xiong⁵, Xuhong Yang⁶, Minglei Wang², and Xiaodong Wang⁷

¹Radiology, General Hospital of Ningxia Medical University, yinchuan, China, ²General Hospital of Ningxia Medical University, Yinchuan, China, ³Radiotherapy, General Hospital of Ningxia Medical University, Yinchuan, China, ⁴Radiology, Yinchuan Hospital of Traditional Chinese Medicine, Yinchuan, China, ⁵GE Healthcare MR Research, Beijing, China, ⁶Ningxia Medical University, Yinchuan, China, ⁷Radiology, General Hospital of Ningxia Medical University, Yinchuan, China

Synopsis

Keywords: Tumors, Cancer, Glioma;True Progression;Pseudoprogression;DKI;IVIMThe differentiation of pseudoprogression from true progression remains a crucial diagnostic dilemma in glioma with postoperative radiation therapy.This work to explore the role of DKI combined IVIM in differentiating true progression and pseudoprogression in glioma. It was concluded that the MK and RK from DKI、D and D* from IVIM can be used as novel imaging biomarkers for Clinical and radiologists in differentiating glioma true progression from pseudoprogression. Combining MK, RK, D and D* may explore as an effective strategy to improve the ability for discriminating glioma true progression and pseudoprogression.

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