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Abstract #1749

Identification of IDH genotype and tumor subtype of adult-type diffuse gliomas based on WHO CNS5 using histogram features of QSM and ADC

Yifan Sun1, Zheting Yang1, Yang Song2, and Rifeng Jiang1
1Fujian Medical University Union Hospital, Fuzhou, China, 2MR Scientific Marketing, Siemens Healthineers Ltd., Shanghai, China

Synopsis

Keywords: Tumors, Quantitative Susceptibility mapping, Glioma; Isocitrate dehydrogenase; WHO CNS5Preoperative prediction of glioma histological features and biological behavior is clinically important. However, few studies reported the histogram analysis of QSM in the isocitrate dehydrogenase (IDH) genotype and subtype of gliomas. In this study, we explored the value of histogram features of QSM and ADC in predicting the IDH genotype and tumor subtype of adult-type diffuse gliomas based on the fifth edition of the World Health Organization Classification of Tumors of the Central Nervous System (WHO CNS5). We found that histogram parameters based on QSM and ADC are significantly related to the IDH genotype, tumor subtype, and proliferation of glioma.

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