Abstract #1754

Preoperative ASL correlates with molecular markers of IDH and HIF-1α in glioma microenvironment and is predictive of patient outcome

Ruiwen Geng¹, Yang Dong¹, and Lizhi Xie²

¹Radiology, The Second Hospital, Dalian Medical University, Dalian, China, ²GE Healthcare, MR Research China, Beijing, China

Synopsis

Keywords: Tumors, Arterial spin labellingThis study retrospectively analyzed the association between arterial spin labeling (ASL) and the molecular markers of isocitrate-dehydrogenase (IDH) mutation and hypoxia-inducible factor (HIF) -1α in glioma. The association of patients’ overall survival (OS) and progression-free survival (PFS) with quantization cerebral blood flow (CBF) from ASL, the imaging parameters from conventional MRI, clinical and pathological parameters were investigated in glioma.

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