Abstract #1755

Characterising glioma heterogeneity with diffusion-relaxation MRI and InSpect

Paddy J. Slator¹, Rui V. Simoes^2,3, Rafael N. Henriques², Tânia Carvalho², Daniel C. Alexander¹, Noam Shemesh², and Andrada Ianus²

¹Centre for Medical Image Computing and Department of Computer Science, University College London, London, United Kingdom, ²Champalimaud Research, Champalimaud Foundation, Lisbon, Portugal, ³Institute for Research & Innovation in Health (i3S), University of Porto, Porto, Portugal

Synopsis

Keywords: Tumors, MicrostructureWe characterise ex-vivo mouse brain tumours with combined T2-diffusion MRI and InSpect, a data-driven unsupervised learning technique that identifies distinct tissue components. We hence reveal heterogeneous tumour structures without imposing a biophysical model.

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