Abstract #1758

Whole-tumor ADC Histogram Analysis in evaluating Tongue Squamous Cell Carcinoma heterogeneity and predicting Cervical Lymph Node Metastases

Xinying Li¹, Ke Xue², Xing Yang^1,3, Yongming Dai², Zhen Tian¹, and Yingwei Wu¹

¹Shanghai Ninth People’s Hospital, affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China, ²MR Collaboration, Central Research Institute, Shanghai United Imaging Healthcare, Shanghai, China, ³Shanghai Pulmonary Hospital, Shanghai, China

Synopsis

Keywords: Head & Neck/ENT, Diffusion/other diffusion imaging techniquesTumor heterogeneity occurred frequently in patients with SCC and associated with poor prognosis. Compared to clinic TNM stage or the histological grade, the histological heterogeneity has not been well addressed yet. Our results clearly demonstrated that higher incidence of CNM was observed in histological hetero-group than that in homo-group. whole-lesion ADC histogram metrics presented lower values in hetero-group and in CNM+ group. ADC75th and kurtosis were two independent prognostic factors for evaluating the CNM status. Whole-tumor ADC histogram offered an approach for detecting intra-tumoral heterogeneity and predicting cervical lymph node metastases status.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.