Abstract #1783

Feasibility of T1/T2/T1ρ MR Multitasking of Arm Muscle for Imaging Amyotrophic Lateral Sclerosis

Matthew Dausch¹, Sen Ma¹, Xianglun Mao¹, Hsu-Lei Lee¹, Yibin Xie¹, Debiao Li¹, Frank Diaz², and Anthony Christodoulou¹

¹Biomedical Imaging Research Institute, Cedaras Sinai Medical Center, Los Angeles, CA, United States, ²Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, United States

Synopsis

Keywords: Quantitative Imaging, Neurodegeneration, MR Multitasking, Amyotrophic Lateral SclerosisAmyotrophic Lateral Sclerosis (ALS) is a neurodegenerative motor disorder that has a need for imaging methods for longitudinal studies. T1/T2/T1ρ MR multitasking is a multiparametric, quantitative, imaging method that shows promise in being a viable tool for this purpose. In this study, we tested the feasibility of a motion weighting modified T1/T2/T1ρ MR multitasking in the arm muscles, evaluating the accuracy and precision of quantitative measurements.

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