Abstract #1787

**Low Volume, Pneumatic Flow Phantom for Validation of Flowing T2* Estimation Using Projection Acquisition with Flow-Encoded Subtraction**

Corina Margain¹, Christopher Sandino², Shreyas Vasanawala³, and Adam Bush¹

¹Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, United States, ²Department of Electrical Engineering, Stanford University, Stanford, CA, United States, ³Department of Radiology, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Quantitative Imaging, Phantoms, non-cartesianBlood-oxygen level is a known biomarker for cardiovascular diseases which can be quantified by T2*-weighted MRI. Challenges with validation and motion have limited the clinical use of T2* oximetry methods. We present a PALMS sequence to measure flowing T2* which was validated using a pneumatically powered, low-volume, continuous flow phantom. Our results suggest that the presence of readout gradients influence T2* during flowing conditions while obliquity influences T2* in all settings conditions.

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