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Abstract #1787

Low Volume, Pneumatic Flow Phantom for Validation of Flowing T2* Estimation Using Projection Acquisition with Flow-Encoded Subtraction

Corina Margain1, Christopher Sandino2, Shreyas Vasanawala3, and Adam Bush1
1Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, United States, 2Department of Electrical Engineering, Stanford University, Stanford, CA, United States, 3Department of Radiology, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Quantitative Imaging, Phantoms, non-cartesianBlood-oxygen level is a known biomarker for cardiovascular diseases which can be quantified by T2*-weighted MRI. Challenges with validation and motion have limited the clinical use of T2* oximetry methods. We present a PALMS sequence to measure flowing T2* which was validated using a pneumatically powered, low-volume, continuous flow phantom. Our results suggest that the presence of readout gradients influence T2* during flowing conditions while obliquity influences T2* in all settings conditions.

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Keywords