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Abstract #1791

Quantitative analysis of the placental structure and function and fetal growth using intravoxel incoherent motion MRI

Dana Schonberger1,2, Daphna Link-Sourani1, Netanell Avisdris1,3, Aviad Rabinowich1,4,5, Bella Specktopr Fadida1,3, Liat Ben-Sira4,6,7, Leo Joskowicz3, Liran Hiersch8, Ayala Zilberman8, and Dafna Ben Bashat1,4,7
1Sagol Brain Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2The Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel, 3School of Computer Science and Engineering, The Hebrew University of Jerusalem, Jerusalem, Israel, 4Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 5Department of Radiology, Tel Aviv Sourasky Medical Center, Israel, Tel Aviv, Israel, 6Division of Pediatric Radiology, Tel Aviv Sourasky Medical Center, Israel, Tel Aviv, Israel, 7Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel, 8Department of Maternal-Fetal Medicine and High Risk Pregnancy Outpatient clinic, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

Synopsis

Keywords: Quantitative Imaging, Perfusion, Intravoxel incoherent motion, IVIMPlacental structural and functional parameters are important for the assessment of placental insufficiency and fetal growth. Here we assessed quantitative measures of placental structural and functional parameters extracted from Intravoxel-incoherent motion (IVIM) with radiomics analysis, in fetuses with growth restriction (FGR) and appropriate for gestational age (AGA). Placental structure (volume and centricity index (CI, umbilical cord insertion location) were correlated with radiomics features of placental perfusion in AGA, and some were found to be significantly different between FGR and AGA, indicating higher functional heterogeneity in FGR. This multi-parametric quantitative placental assessment may improve identification of FGR fetuses.

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