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Abstract #1796

Accelerated Sampling Strategy for High-resolution 3D T1rho Dispersion MRI with 4D Dynamic Radial Acquisitions

Gregory Peng1, Can Wu2, Jafari Ramin3, Yansong Zhao3, and Qi Peng1
1Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, United States, 2Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 3Philips Healthcare, Cambridge, MA, United States

Synopsis

Keywords: Quantitative Imaging, Quantitative Imaging, T1rho dispersion imagingT1ρ dispersion imaging based on repeated T1ρ measurements at multiple spin-lock frequencies allows characterization of different dynamic processes of tissues. The clinical potential of these techniques is, however, limited by the total scan time needed to obtain reliable and consistent quantitative measurements. In this abstract, we propose the application of a 4D dynamic sequence with radial acquisitions in combination with an accelerated data-point sampling strategy to achieve efficient coverage of the high-dimensional data space in T1rho dispersion MRI, which leads to high-resolution 3D T1rho dispersion imaging acquired within clinically acceptable scan duration of ~5 minutes.

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Keywords